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・ Glycoside hydrolase family 37
・ Glycoside hydrolase family 38
・ Glycoside hydrolase family 39
・ Glycoside hydrolase family 4
・ Glycoside hydrolase family 42
・ Glycoside hydrolase family 43
・ Glycoside hydrolase family 44
・ Glycoside hydrolase family 45
・ Glycoside hydrolase family 46
・ Glycoside hydrolase family 47
・ Glycoside hydrolase family 48
・ Glycoside hydrolase family 49
・ Glycoside hydrolase family 5
・ Glycoside hydrolase family 52
・ Glycoside hydrolase family 53
Glycoside hydrolase family 56
・ Glycoside hydrolase family 57
・ Glycoside hydrolase family 59
・ Glycoside hydrolase family 6
・ Glycoside hydrolase family 61
・ Glycoside hydrolase family 62
・ Glycoside hydrolase family 63
・ Glycoside hydrolase family 65
・ Glycoside hydrolase family 66
・ Glycoside hydrolase family 67
・ Glycoside hydrolase family 68
・ Glycoside hydrolase family 7
・ Glycoside hydrolase family 70
・ Glycoside hydrolase family 71
・ Glycoside hydrolase family 72


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Glycoside hydrolase family 56 : ウィキペディア英語版
Glycoside hydrolase family 56

In molecular biology, glycoside hydrolase family 56 is a family of glycoside hydrolases.
Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.〔(Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999. )〕 This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,〔(Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999. )〕 and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.〔(CAZypedia, an online encyclopedia of carbohydrate-active enzymes. )〕
Glycoside hydrolase family 56 (CAZY GH_56 ) includes enzymes with hyaluronidase activity. The venom of ''Apis mellifera'' (Honeybee) contains several biologically-active peptides and two enzymes, one of which is a hyaluronidase. The amino acid sequence of bee venom hyaluronidase contains 349 amino acids, and includes four cysteines and a number of potential glycosylation sites.〔 The sequence shows a high degree of similarity to PH-20, a membrane protein of mammalian sperm involved in sperm-egg adhesion, supporting the view that hyaluronidases play a role in fertilisation.〔
PH-20 is required for sperm adhesion to the egg zona pellucida; it is located on both the sperm plasma membrane and acrosomal membrane. The amino acid sequence of the mature protein contains 468 amino acids, and includes six potential N-linked glycosylation sites and twelve cysteines, eight of which are tightly clustered near the C-terminus.〔
==References==


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